+49 5461 7089089

MP-SPR Navi 200 OTSO
  • MP-SPR Entry-Level Instrument
  • Manual Sample Feeding
  • Full flow cell flexibility
  • Up to 4 wavelengths

The MP-SPR NaviTM 200 OTSO (named after the Finnish cub bear) offers the inexpensive basic device in the basic configuration as an entry into the MP-SPR world.

In the most affordable version, the 2-channel device comes with one laser and can be upgraded to up to four wavelengths. Different flux cells are available for the various application areas. The open design also makes it an ideal and affordable tool for teaching. 

Upgrading to the automated 210A VASA is easily possible long after procurement. 


MP-SPR Navi 200 OTSO

  • Goniometric SPR optics with wide angle curve acquisition
  • Manual Sample Feeding
  • 2 Measurement Channels with Parallel Injection
  • 1-4 Lasers
  • Optional Degassing Unit
  • Software: NaviTM-Control and DataViewer included, with PureKineticsTM-Functionality
  • LayerSolver and TraceDrawer optional
  • Various Flow Cells available, e.g. for LS, MS, Electrochemistry, Light Coupling, Fluorescence coupling
  • Possibility to Upgrade to 210A VASA

For the many applications of the MP-SPR ...

... and extensive detailed information as well as a keyword search, please use the links to the manufacturer's page of BioNavis here below.





With PureKinetics™ feature for high quality kinetics, MP-SPR is a powerful and sensitive tool for direct measurements of small molecules.



MP-SPR helps you to measure biomembrane interaction kinetics as well as underlying structural changes.



Whether you develop metal, silica, polymer nanoparticles or work with DNA polyplexes, liposomes, viruses or microvesicles, MP-SPR is an excellent choice for drug delivery studies - from real-time targeting studies to real-time internalization with the same instrument.



MP-SPR enables to move from drug-target measurements, through drug-membrane interactions all the way to drug-cell interactions. Differentiate internalization from permeation in real-time and label-free. Study cell attachment on different coatings.



Antibody-antigen interaction affinity and kinetic measurements can be performed in diverse liquids including complex liquids such as serum or saliva.



Biosensor development


MP-SPR can be combined with electrochemistry to measure catalytic interactions, electroswitching surfaces and also to develop electrochemical biosensors.  

Biosensor Development

From nanoparticle-based competitive assays through electrochemical sensors to direct assays, MP-SPR shows all the steps of your assay may you develop it on top of glass, polymer, silica or metal surfaces! More...

Gas sensor development MP-SPR works also with gas samples - from 2 dalton hydrogen up to vapours. More..


Biomaterials and coatings

Biomaterials MP-SPR measures interactions on polymers up to 5 µm thick, which makes it the most sensitive label-free technique for biomaterial interaction studies and layer characterization. Therefore, MP-SPR also helps with formulations for controlled drug release, novel coatings for cell and tissue engineering as well as industrial coatings.

Unique Multi-Parametric Surface Plasmon Resonance (MP-SPR) instruments can extend applicability of SPR also to clinically relevant complex liquids, such as 100 % serum, plasma, urine, bacteria and cells.

200 OTSO

Measurement principle

Real-time and label-free Multi-Parametric Surface Plasmon Resonance (MP-SPR) is based on a true goniometric SPR arrangement with a rotating detector. Exceptionally wide angular range 40-78 ̊ is measured, real angular resolution 0.001 ̊.

Liquid handling  

Controlled buffer flow conditions with peristaltic pump. Flow rate range from 10 μl/min up to 400 μl/min. Two flow channels and manual sample injector. Instrument can be later upgraded with dedicated autosampler to a 210A VASA.

Sample consumption

Typical required sample volume 200-500 μl. Sample volume can be further varied by changing sample loops.

Wavelength of light

Standard 670 nm in both flow channels.
Up to 4 wavelengths per channel available on request.

Refractive index range

1.00-1.40 (measurement bulk environment) which can be extended with additional wavelength
Layers that MP-SPR can measure can have much higher RI such as diamond like carbon (2.7) and inorganic crystals.
MP-SPR determines also complex refractive index of liquids, gases and solid layers.


Measurements can occur in gas and liquids. Liquids can be aqueous solutions or organic liquids such as ethanol and acetonitrile.

Mode of operation

Angular Scanning mode, or “MP-SPR mode”: scanning across a range of angles providing full SPR curve and multiple parameters. Several sensograms can be distinguished from the full curve, such as PureKineticsTM. Sampling rate depends on selected angular range and resolution, typically less than 2 seconds.

Fixed Angle mode, “traditional SPR mode”: measurement at a single angle, providing time – intensity sensogram. Mode for fast kinetic studies - sampling rate from 1ms

Measurement Range

Thickness from Ångströms to micrometers (true range depends on refractive index of the material). Kinetics: ka = 103 – 108 1/(M*s), kd = 10-7 – 0.1 1/s, KD = 10-3 – 10-12 M


Smallest detected molecule: in gas Hydrogen (2 Da); in liquid small molecules <100 Daltons


Short-term noise 0.3 μRIU, Baseline drift (long term) < 1μRIU/min.

Temperature Measurement temperature range from 15 – 45 ̊C (7 ̊ below to 20 ̊C above ambient).
Prism Elastomer supported prism for quick sensor exchange and easy maintenance
Flow Cells

Flow cells can be easily exchanged with a single release button.
Standard: PDMS material flow cell with a volume of 1 μl/channel.
Optional flow cells: SPR305-MS: high chemical resistance PEEK flow cell with wider tubing diameter, SPR321-EC: Electrochemical flow cell, SPR310-GS: Gas flow cell, SPR302-LS for fast kinetic studies, or request a custom flow cell!

Software Unlimited MP-SPR NaviTM Control and DataViewer software. Export data easily to Excel or use our dedicated analyzing tools.
Optional LayerSolverTM fitting tool for layer characterization and/ or TraceDrawerTM software for kinetic analysis.

Fluidic parts are easily exchanged. Maintenance service contract available if so desired.

Computer Requirements Win 7, Win 8.1 or Win 10, 1 x USB 2.0, 4GB RAM, 10GB hard disk space (1GB for installation + space for measured data)
Dimensions & Weight

W 33 x H 42 x D 39 cm (13” x 17” x 15”), 11 kg (24 lbs)

Power Requirements 100-240V, 50/60Hz, Max. 40W